2015 Jun;22(2):62-5. doi: 10.1016/j.tracli.2015.04.002. 1995 Sep;35(9):734-7. doi: 10.1046/j.1537-2995.1995.35996029156.x. Using another's blood must first start with donation of blood.

The term allogeneic refers to blood products manufactured from blood donations from healthy subjects (blood donors) which are intended for transfusion to different subjects (blood recipients).

Some properties of allogeneic blood products in common use, 4-10 units pooled into a single container, Reconstituted with diluent, then transfused, CPD-A1 = Citrate - Phosphate - Dextrose - Adenine a standard allogeneic blood product.

The two remaining clinical situations where whole blood is still preferentially requested for transfusion are patients with trauma requiring multiple transfusions and cardiac surgery, particularly pediatric cardiac surgery. doi: 10.1002/14651858.CD002042.pub3.  |  NIH

Directed donations are generally neither encouraged nor discouraged by blood collection facilities. NLM The mean hospital stay was 1.9 days. The effects of conservative transfusion triggers on functional status, morbidity and mortality, particularly in patients with cardiac disease, need to be tested in further large clinical trials. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. This site needs JavaScript to work properly. However, they differ in that the intended recipient is identified at the time of donation. Trials were included where intervention groups were assigned on the basis of a clear transfusion 'trigger', described as a haemoglobin (Hb) or haematocrit (Hct) level below which an RBC transfusion was to be administered.  |  USA.gov. Write For Us

A different type of volunteer blood donor is known as a directed donor, and the donation as a 'directed donation'. Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC.

For patients aged not more than 60 years, receiving autologous blood was associated with lower risk of BCR (HR, 0.82 [95% CI, 0.68‐0.99]; p = 0.034). These are simple solutions containing citric acid to chelate calcium and, therefore, prevent activation of the coagulation system and glucose to allow red cells to metabolize during in vitro storage (e.g., citrate-phosphate-dextrose or CPD). 2020 Feb 21;17(5):620-625. doi: 10.7150/ijms.33954. The allogeneic blood supply in the United States, much of Europe and Japan is predominantly collected from what are known as 'volunteer blood donors'. Main results: Most clinical practice guidelines recommend restrictive red cell transfusion practices, with the goal of minimising exposure to allogeneic blood (from an unrelated donor).

Red blood cell transfusion for people undergoing hip fracture surgery.

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Trials were identified by: computer searches of the Cochrane Central Register of Controlled Trials (the Cochrane Library Issue 3, 2009), OVID MEDLINE (1966 to August 2009), Current Contents (1993 to November 2004), and the Web of Science (2004 to August 2009).  | 

Restrictive transfusion strategies were associated with a statistically significant reduction in the rates of infection (RR=0.76; 95% CI 0.60 to 0.97). Get the latest research from NIH: https://www.nih.gov/coronavirus.

Data collection and analysis:

Franchini M, Marano G, Veropalumbo E, Masiello F, Pati I, Candura F, Profili S, Catalano L, Piccinini V, Pupella S, Vaglio S, Liumbruno GM. Directed donor blood products are allogeneic blood products which meet all the requirements for, -plasma ^ cryoprecipitate; cryo poor plasma -platelets, Bone Marrow Peripheral Blood Umbilical Cord Fetal Hepatocytes, Liquid (e.g., red cells, platelets) Frozen (e.g., plasma) Lyophilized (e.g., derivatives), Table 2.1. Very severe outcomes associated with autologous blood donation. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Stem cell transplant can be either allogeneic or autologous.

Please enable it to take advantage of the complete set of features! 2012 Apr 18;4(4):CD002042. The red cell concentrate can be stored in the anticoagulant plasma alone (CPD red blood cells; CPD-A1 red blood cells), or a crystalline solution can be added, which contains glucose and stabilizers to maintain the quality of red cells during the storage period (Adsol®, Nutricell®, or Optisol®). To examine the evidence for the effect of transfusion thresholds on the use of allogeneic and/or autologous blood, and the evidence for any effect on clinical outcomes. Examples of these processes are pasteurization i.e., heating to 60° C for ten hours; various separation steps, e.g., gel filtration or micro-filtration, and chemical treatments such as solvent detergent exposure. However, red cells (or less commonly platelets) may also be stored in the frozen state using cryoprotective agents; and certain blood derivatives, such as one preparation of immunoglobulin and all albumin preparations, are stored in the liquid state.

Without any doubt, allogeneic RBC transfusions are crucial in the treatment of patients with trauma and major blood loss. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/.

eCollection 2020.

Demographic data, BMI, preoperative diagnosis, type of anesthesia, medical comorbidities, preoperative autologous blood donation, allogeneic blood transfusion, and pre- and post-operative complete blood count (CBC) including hematocrit (Hct); and Hb levels were evaluated.

Seventeen trials involving a total of 3746 patients were identified. Surg Today. 2015 May;42(3):181-92. doi: 10.1159/000371614. The maximum duration of storage for red cells (at 1-6°C) under such circumstances is currently 42 days (Chapter 27). Donors > 40 years old had 87.9 percent of the VSOs, and donors > 60 years old had 48.5 percent. It is anticipated that many such products will be approved for use by late 1999.

Directed donor blood may be transfused to a recipient other than the intended recipient, if the latter does not require transfusion, a practice "called crossover".

Summary – Allogeneic vs Autologous Transplant. This accounts for the delay in availability since it takes between 15-30 minutes to either thaw frozen products, or to reconstitute lyophilized products prior to transfusion. Cochrane Database Syst Rev. Homologous, or more correctly allogenic, blood transfusions involves someone collecting and infusing the blood of a compatible donor into him/herself.

Each such donation has a unique identification (unit number or lot number).

These are manufactured from a plasma pool usually containing between 5,000 and 20,000 donations. Certain blood products are manufactured and stored in the lyophilized state; examples are some immunoglobulin preparations and coagulation factor concentrates.

Epub 2013 Jun 3. The incidence of VSOs for allogeneic donation was 1 (0.0005%) in 198,119 and that for autologous donation was 1 (0.006%) in 16,783 (p < 0.001).

Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion.

There are two types of stem cell transplants: autologous and allogeneic.Each of these stem cell procedures has its own distinct process. Transfusion Challenges in Patients with Hematological Malignancies in Sub-Saharan Africa: A Prospective Observational Study from the Uganda Cancer Institute.

Estcourt LJ, Malouf R, Trivella M, Fergusson DA, Hopewell S, Murphy MF.

Other names used regionally to describe these products are; "regular blood", "shelf blood" or "banked blood".

In countries with inadequate screening of donor blood, the data may constitute a stronger basis for avoiding transfusion with allogeneic red cells. Int J Med Sci. Allogeneic versus autologous blood transfusion and survival after radical prostatectomy Heather J. Chalfin , 1 Steven M. Frank , 2 Zhaoyong Feng , 1 Bruce J. Trock , 1 Charles G. Drake , 1, 3 Alan W. Partin , 1 Elizabeth Humphreys , 1 Paul M. Ness , 4 Byong C. Jeong , 1 Seung B. Lee , 1 and Misop Han 1

2020 May 7;2020:8246309. doi: 10.1155/2020/8246309. Riga A, Sapey T, Bacanu M, Py JY, Dehaut F. Transfus Clin Biol.