Computed tomography (CT) scan of the abdomen (July 9, 2014): abscess in the left psoas muscle.
Ruptured aortic aneurysm due to Mycobacterium bovis BCG with a delayed bacteriological diagnosis due to false negative result of the MPB 64 immunochromatographic assay. There is no consensus yet regarding treatment of infectious arterial ruptures. [HIV-infection, AIDS and BCG vaccination]. HHS Krysztopa-Grzybowska K, Paradowska-Stankiewicz I, Lutyńska A. Clin Infect Dis. Abdominal aortic aneurysmal and endovascular device infection with iliopsoas abscess caused by Mycobacterium bovis as a complication of intravesical bacillus Calmette-Guérin therapy. J Clin Immunol. Needle aspiration is thus the treatment of choice for suppurative local complica-tions of BCG vaccination; incision and drainage of BCG complications is not recommended.18 Correspondence: Marjolijn Leeman, MD, Sint Franciscus Gasthuis, Kleiweg 500, Rotterdam 3045 PM, The Netherlands, Department of Surgery, Sint Franciscus Hospital, Rotterdam, The Netherlands, Intravesical administration of bacille Calmette-Guérin (BCG) is considered to be the therapy of choice for treating superficial bladder carcinoma. A 63‐year‐old man underwent a transurethral resection of bladder tumor for a grade 3, stage pT1 transitional cell carcinoma. A Case of Tuberculous Prostatitis with Abscess. After a 1-day admission to the intensive care unit, the patient was transferred to the department of surgery. The biopsies suggested recurrent carcinoma in situ, so weekly intravesical BCG instillations (medac, Glasgow, UK) were commenced at a concentration of 81 mg in 40 mL saline. During the treatment, our patient experienced general malaise, weight loss, subfebrile temperatures, and night sweats. | If you do not receive an email within 10 minutes, your email address may not be registered, Six days postoperatively, the patient was discharged with rifampicin and isoniazid.
The etiology and management of acute prostatitis.
2018 Apr 4;9:629. doi: 10.3389/fimmu.2018.00629. Arterial complications caused by BCG instillations are rare; nevertheless, arterial aneurysms are a recognized complication. Created from a live attenuated strain of, Bacille Calmette-Guérin (BCG) is a live attenuated strain of. X-Linked Chronic Granulomatous Disease: Initial Presentation with Intracranial Hemorrhage from Vitamin K Deficiency in Infant.
BCG-induced psoas abscesses without vascular complications are more often described. Disseminated disease usually occurs in people with impaired immunity, in whom it is often fatal. By continuing you agree to the, https://doi.org/10.1016/j.jvs.2017.02.038, Psoas abscess after bacille Calmette-Guérin instillations causing iliac artery contained rupture, View Large Rev Infect Dis.
A computed tomography (CT) scan of the abdomen in 2014 revealed multiple abscesses in his liver, kidney, vertebrae (T2 and L3), left iliopsoas muscle, and mediastinum, as shown in, To stop life-threatening hemorrhage, placement of an endovascular covered stent was chosen, using part of the Endurant II (Medtronic, Santa Rosa, Calif) stent (ETLW1613C93EE). Tuberculous Prostatic Abscess with Prostatorectal Fistula after Intravesical Bacillus Calmette-Guérin Immunotherapy. We describe the case of a patient with a history of BCG instillations presenting with an arterial rupture of his left iliac artery due to an abscess in the iliopsoas muscle. There was no evidence of TB elsewhere. Use the link below to share a full-text version of this article with your friends and colleagues. 2018 Jun 24;2018:7041204. doi: 10.1155/2018/7041204. Epub 2017 Aug 7. eCollection 2018. 1989 Mar-Apr;11(2):335-7. doi: 10.1093/clinids/11.2.335. Bacillus Calmette-Guérin vaccine related lymphadenitis in children: Management guidelines endorsed by the Saudi Pediatric Infectious Diseases Society (SPIDS). Bacillus Calmette-Guerin (BCG) is a live attenuated strain of Mycobacterium bovis that has been used to treat urothelial carcinoma since 1976, and has been reported to eradicate disease in more than 70% of patients with in situ and stage I disease.
BCG should never be given to people who are known to be infected with HIV, but the risk of complications in children born to HIV infected mothers is low. In 1997, Gupta et al found 27 patients with tuberculous psoas abscesses. Sullivan KE, Bassiri H, Bousfiha AA, Costa-Carvalho BT, Freeman AF, Hagin D, Lau YL, Lionakis MS, Moreira I, Pinto JA, de Moraes-Pinto MI, Rawat A, Reda SM, Reyes SOL, Seppänen M, Tang MLK. We describe the case of a 71-year old cachectic white man who visited our emergency department in September 2014 reporting fever, night sweats, and progressive abdominal pain in the lower left quadrant, which had started 6 weeks before presentation.
Multiparametric MRI features of granulomatous prostatitis and tubercular prostate abscess. Learn about our remote access options, Department of Urology and General Surgery, Whiston Hospital, Merseyside, UK. Please check your email for instructions on resetting your password. Carbasalate calcium was prescribed as anticoagulation therapy; 3 months after the procedure, the patient recovered from hemorrhage and was in stable clinical condition with a good nutritional status. Accepted: Bacille Calmette-Guérin (BCG) is a live attenuated strain of Mycobacterium bovis , originally produced to serve as a vaccine against tuberculosis.
The distribution of BCG prostatitis: A clue for pathogenetic processes?. It has been described that aneurysms can occur in varying locations, not always in connection with an abscess. He followed up in clinic one month later for a surveillance cystoscopy that was negative. BCG sepsis has a mortality rate of one death for every 12,500 patients treated with intravesical ... Scrotal ultrasound demonstrated a left scrotal abscess. 2000 Sep;31 Suppl 3:S71-4. doi: 10.1086/314075. Lymphadenopathy responds poorly to antimicrobial treatment and surgery may be needed for suppurating or discharging lesions to hasten recovery and give a good cosmetic result. Intravesical BCG is an effective treatment option for the management of recurrent transitional cell neoplasia and carcinoma in situ.1 It was first used intravesically in 1976 as a non‐specific immune system stimulant.2, Granulomatous protatitis is a well recognized complication of BCG immunotherapy, but is probably more common than symptoms would suggest.3 This is only the second report of granulomatous prostatitis leading to a tubercular abscess after BCG treatment. eCollection 2018. 2007 Jan 2;25(1):14-8. doi: 10.1016/j.vaccine.2006.07.020. Journal de Radiologie Diagnostique et Interventionnelle. A planned midline laparotomy was performed with excision of the stent and reconstruction of the common iliac artery using a reversed superficial femoral vein. This therapy is generally safe but may rarely be complicated by granulomatous infection within the urinary tract. Acid‐fast bacillus with Ziehl–Neelsen staining (×1000).
In the case of arterial rupture, we suggest endovascular treatment with a covered stent to temporarily control the bleeding, with planning of explantation of the stent and repair with a deep vein for definite treatment. Complications of bacille Calmette-Guérin (BCG) vaccination are uncommon. 2017, Received: Polymerase chain reaction (PCR) amplification and cultures of this biopsy specimen remained negative for the presence of mycobacteria. Long-term results of the treatment of aortic graft infection by in situ replacement with femoral popliteal vein grafts. The patient refused ultrasound, demanding surgery. Fewer than one in 1000 people vaccinated develop significant local reactions, and serious disseminated disease develops in fewer than one in a million. © 2017 by the Society for Vascular Surgery.
Front Immunol. However, approximately 8% of patients have to stop BCG instillation as a result of its complications. The patient had no history of tuberculosis (TB). An urgent transurethral prostatic resection produced copious white secretion. Disseminated tuberculosis with prostatic abscesses in an immunocompromised patient—A case report and review of literature. Postoperatively, the patient was brought to the intensive care unit.
They usually result from faulty technique, including the accidental intracutaneous injection of the stronger percutaneous vaccine, or poor selection of subjects for vaccination. Richardus R, van Hooij A, van den Eeden SJF, Wilson L, Alam K, Richardus JH, Geluk A. Bacillus Calmette-Guérin (BCG) Infection Following Intravesical BCG Administration as Adjunctive Therapy For Bladder Cancer. BCG infection.4 Surgical treatment Drainage Needle aspiration of mycobacterial abscesses reduces the risk of developing a draining sinus compared with incision and drainage. To the best of our knowledge, this is the first case report describing arterial rupture after BCG instillation without the presence of an aneurysm. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, Management of complications of Bacillus Calmette‐Guérin immunotherapy in the treatment of bladder cancer, Intravesical Bacillus Calmette‐Guérin in the treatment of superficial bladder tumours, Sanders WH. Localised complications--which include hypersensitivity reactions, abscesse … December 19, After 5 weeks of treatment (during which no traumatic catheterizations were recorded) the patient complained of perineal pain, dysuria, tenesmus and strangury. This site needs JavaScript to work properly. Hesseling AC, Marais BJ, Gie RP, Schaaf HS, Fine PE, Godfrey-Faussett P, Beyers N. Vaccine.
Samples from the excised stent were taken for culture and PCR.