[Medline].  RP Clarithromycin: review of a new macrolide antibiotic with improved microbiologic spectrum and favorable pharmacokinetic and adverse effect profiles. Santos-Juanes J, Galache C, Martinez-Cordero A, et al.

Exogenous coproporphyrin III production by Corynebacterium aurimucosum and Microbacterium oxydans in erythrasma lesions. Erythrasma can mimic a low-grade dermatitis, but it is actually a minor superficial bacterial infection.

19(5):313-6. The slowly enlarging patches of pink-to-brown, dry skin are caused by an infection with the bacterium called Corynebacterium minutissimum.

Inci M, Serarslan G, Ozer B, et al. 1995-1996. This website also contains material copyrighted by 3rd parties. Seek medical treatment if you have symptoms of a serious drug reaction that can affect many parts of your body. Erythromycin is the treatment of choice for erythrasma. Topical treatment with 2% erythromycin gel132 or an aqueous solution of 2% clindamycin hydrochloride can also be effective. 132(6):716-7.

2006 Jun. Store at room temperature away from moisture and heat. I. Ultrastructural evidence for a keratolytic action experted by Corynebacterium minutissimum. Br J Dermatol. 3 Applying topical clindamycin 1% gel or cream to the affected area two to three times a day for two to four weeks effectively eradicates most infections. We chose to give our patients a single 1-g dose of clarithromycin to treat their erythrasma. This cutaneous infection manifests as well-demarcated, reddish brown patches and plaques located in moist intertriginous zones. The parent drug and its metabolites are excreted in both the urine and feces.3, Drug interactions include carbamazepine, theophylline, oral contraceptives, and an enhancement of glucocorticosteroid effects. Erythrasma caused by Corynebacterium minutissimum is a common disease, occurring more often in men and with a predilection for the intertriginous areas (Table 49.7). Carlos Nicolas Prieto-Granada, ... Martin C. It inhibits bacterial growth, possibly by blocking dissociation of peptidyl t-RNA from ribosomes, causing RNA-dependent protein synthesis to arrest.

 KM The newer macrolides: azithromycin and clarithromycin.

Do not use anti-diarrhea medicine unless your doctor tells you to. Corynebacterium minutissimum bacteremia in an immunocompetent host with cellulitis. Use of this site constitutes acceptance of Skinsight's terms of service and privacy policy. 60 (Pt 7):1038-42. Erythrasma presents as sharply demarcated patches of red or red-brown skin covered by a fine white scale (Fig. Lesions often begin as pink or red (Figure 1) and over time develop a brown discoloration. Malakoplakia has been reported on rare occasions in the female genital tract, including the vulva59,60 and, more often, the vagina.61,62 Diagnosis of vaginal malakoplakia has been made by cytology, including fine-needle aspiration cytology.63,64, James E. Fitzpatrick MD, ... W. Lamar Kyle MD, in Urgent Care Dermatology: Symptom-Based Diagnosis, 2018. Data sources include IBM Watson Micromedex (updated 1 Oct 2020), Cerner Multum™ (updated 1 Oct 2020), Wolters Kluwer™ (updated 30 Sep 2020) and others.

Mattox TF, Rutgers J, Yoshimori RN, Bhatia NN. A very characteristic picture is seen in which there is virtually no host response but the changes are limited to the stratum corneum. [Medline].

[Medline]. Clindamycin is used to treat serious infections caused by bacteria.

Arch Dermatol.

2008 Jul-Aug. 99(6):469-73.

Diagnosis is primarily serologic, but nucleic acid detection techniques are more sensitive and specific. Halvaee S, Daie Ghazvini R, Hashemi SJ, Zibafar E, Yekaninejad S, Geramishoar M, et al. Erythrasma Treated With Single-Dose Clarithromycin. Arch Dermatol.

Penton PK, Tyagi E, Humrighouse BW, McQuiston JR.

Photodermatol Photoimmunol Photomed. The etiology of rosacea remains somewhat controversial and is considered to be multifactorial, depending on the phase of disease. Ruba Faik Bahhady, MD Senior Specialist, Department of Dermatology, American University of Beirut Medical CenterDisclosure: Nothing to disclose. Romanowsky-stained air-dried smears from the ulcer bed demonstrate numerous intracytoplasmic, short bacilli within macrophages.47 Rarely the organisms are identified on Pap smears.49 Biopsy of the ulcer base, performed for smear-negative cases, should be stained with Giemsa or Warthin-Starry stain.50 A PCR test has been developed for granuloma inguinale.51 Ulcers caused by multiple infectious agents have been reported.52, Tuberculosis of the vulva is the rarest form of genital tuberculosis and is usually associated with foci of infection elsewhere in the genital tract.53 Hypertrophic lesions with sinus formation may develop.54,55 Surgery may be necessary in conjunction with antituberculosis drugs.56 Necrotizing granulomas are found on biopsy. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1MjUzMi1tZWRpY2F0aW9u. One gram in divided doses is usually given daily for 5 days. All patients tolerated this well with 1 patient experiencing mild abdominal cramping. INTRODUCTION.

Binding is reversible in nature. We use cookies to help provide and enhance our service and tailor content and ads.

51(6):444-7.

41(1):103-5. Infections usually occur after puberty. Get emergency medical help if you have any signs of an allergic reaction to clindamycin: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Maria S Bou Sleiman, MD Resident Physician, Department of Dermatology, American University of Beirut Medical CenterDisclosure: Nothing to disclose. 1985 Jan. 69(1):29-31.

Exogenous coproporphyrin III production by Corynebacterium aurimucosum and Microbacterium oxydans in erythrasma lesions. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. Genome Announc.