Comparison of granulocyte concentrate storage at 6 degrees C versus room temperature indicated at 24 hr an improved (p greater than 0.02) but still abnormal (p greater than 0.02) chemotactic response with 24 degrees C storage and at 48 hr no difference in migration but a slight advantage in bacterial killing at 6 degrees C storage. Storage: Granulocytes expire after 24 hours . Frequently asked questions | List of available courses 1 - 6 degrees Celsius, 12 hours - 20 degrees Celsius, 48 hours: 1 - 6 degrees Celsius, 24 hours 20 - 24 degrees Celsius, 24 hours .

The proper storage requirements for granulocyte concentrates is: Please select the single best answer. They are stored at room temperature, like platelets, but they should not be continuously agitated, unlike platelets. Granulocytes have pretty much the shortest shelf life of any product that we collect directly from donors. Dose: The dose is a single granulocyte transfusion per day. An animal study of in vivo granulocyte posttransfusion kinetics and localization demonstrated similar, near normal recovery and survival of granulocytes stored at 4 and room temperature for up to 24 hours, but the study suggested that after 24 hours of storage, granulocytes preserved at 4 were superior with respect to both posttransfusion recovery and migration into an inflammatory locus.43 A subsequent study in humans that em- GRANULOCYTE STORAGE 29 ployed only 4 storage …

1. They should be transfused “as soon as possible” after collection, but definitely within 24 hours of collection. A dose is given daily until granulopoiesis returns, the infection is controlled, the patient is moribund, or a contraindication develops Indications for Granulocyte Concentrate Transfusion.