Base text and orthography is the Nestle 1904 Greek New testament, courtesy of: https://sites.google.com/ site/nestle1904/. 27, 2011. All Rights Reserved. 12 Rubach MP, Bender JM, Mottice S et al.

Although it is not known how H. influenzae enters the bloodstream, it is possible that a co-existing viral or mycoplasma infection of the upper respiratory tract may be a contributing factor.4, In general, H. influenzae disease is considered to be minimally contagious, however, if a person has close contact to someone who is infected with or is carrying H. influenzae, transmission can occur.5 Hib has the potential to spread quickly in populations in enclosed quarters, such as families, institutional settings, and daycare centers.6 Prior to the introduction of Hib vaccines in the United States, health officials had identified a seasonal pattern to Hib, with the first peak between the months of September and December, and the second peak between March and May.7, In the United States, before Hib vaccines became available, approximately two-thirds of all cases of Hib invasive disease affected infants and children under 15 months of age 8 and 85 percent of cases occurred in children under the age of 5.9 Following the introduction of the Hib vaccine, the burden of invasive H. influenzae disease has shifted from children to adults, and most particularly seniors over the age of 65.10 11 A 2011 published study found that between 1998 and 2008, 51 percent of invasive H. influenzae cases involved adults over the age of 65.

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9 FDA ActHIB Product Insert Dec. 20, 2018, 10 FDA Hiberix Product Insert Apr. Meningitis …

8 CDC Haemophilus influenzae type b – Pathogenesis Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book). H. influenzae type b (Hib) is transmitted by direct contact with respiratory secretions and enters the body through the upper respiratory tract. 2 CDC Haemophilus influenzae type b – Pathogenesis Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book). Please look for them carefully. Where either NA or SBL render the word order differently, the NE order is maintained, with the variant noted as follows: «NE Text» ⇔ «NA and / or SBL text», Variants in compound words are noted as follows, Compound ‿ Word or Compound¦word,