Crusts disappear and pain resolves after 2 to 3 months, while leukotrichia persists.

An absence of pigment, partial or total, in the skin. Depigmentation may wax and wane but is usually permanent. One approach, repigmentation, can be achieved successfully in most patients only by PUVA treatment. The diagnosis is usually made based on the clinical appearance alone, but oral exfoliative cytology has been used as a diagnostic aid.[3]. Absence of pigment in the epidermis results in pure white patches of skin that are susceptible to sunburn.

Vitiligo affects all races and geographic areas with a frequency of 0.3–0.5% (Birlea et al., 2012). of the dorsal midline. The homozygous state results in a nonviable embryo that is resorbed in early gestation. genetic loss of pigment. Tissue biopsy is not indicated, but when taken, the histologic appearance is one of increased epithelial thickness, broadening and eleongation of the rete ridges, parakeratosis and intracellular edema of the spinous layer. Patients without a history of known susceptibility factors for basal cell carcinoma were asked about the details of their use of hair dyes. It occurs in about 70-90% of black skinned adults and about 50% of black skinned children. Generalized vitiligo (GV), the most common subtype, occurs with equal frequency in males and females and may manifest at any time in life, with the average age of onset of 24 years (Spritz, 2010). It shows an epidermal basal layer completely devoid of melanocytes in the center of the lesions (Le Poole et al., 1993a); cells expressing melanocyte markers are sometimes observed at the margins of lesions. J.D. No specific treatment is currently available, D.N. Three patients used paint-on henna tattoos and about 1 week later developed localized hypertrichosis over the same area as the tattoo, which resolved spontaneously within 34 months [21A]. Repigmentation by PUVA involves close interaction of melanocytes and keratinocytes. Less often, the labial mucosa, the palate or the floor of mouth may be affected. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. They may in some cases be post-inflammatory, autoimmune, neural or toxic. The term is derived from the Greek words λευκός leukós, "white" and οἴδημα oídēma, "swelling".

Leukoedema is a blue, grey or white appearance of mucosae, particularly the buccal mucosa (the inside of the cheeks); it may also occur on the mucosa of the larynx or vagina. [2] The differential diagnosis is with leukoplakia, oral candidiasis, oral lichen planus, white sponge nevus, morsicatio buccarum,[3] hereditary benign intraepithelial dyskeratosis and dyskeratosis congenita.

Typical clinical findings and absence of preceding skin damage. No practical treatment exists, and tattooing seldom is indicated for leukoderma because cosmetics rarely are of concern. Medical Definition of Leukoderma. Ineffective. In Veterinary Medicine (Eleventh Edition), 2017. Subsequent studies by Lerner et al. Localized depigmentation around the commissures of the lips and tail base may be due to the effect of chemicals contained in rubber tack such as bit guards and crupper straps. Contact leukoderma has been described after the use of agents such as monobenzyl ether of hydroquinone, phenol, and catechol derivatives. leukoderma acquisi´tum centri´fugum a pigmented nevus surrounded by a ring of depigmentation; see also halo nevus. Synonym: achromoderma, hypomelanosis, leukopathia, leukopathy. Leukoderma is a common finding in horses, particularly in areas of tack damage. ˌleucoˈdermal, ˌleucoˈdermic, ˌleukoˈdermal, ˌleukoˈdermic adj. Hyperesthetic leukotrichia: Condition of unknown etiology that is characterized by the development of single or multiple very painful crusts on the dorsal midline from withers to tail. Management systems that keep young calves and heifers tied with baling twine have a high incidence of this lesion appearing as a rather circumferential ring of white hair in the midcervical region. Loss of pigmentation of hair may follow inflammatory injury or may have an inherited basis. Danny W. Scott, in Rebhun's Diseases of Dairy Cattle (Third Edition), 2018. Condition. None proven as effective. Generalized symmetric vitiligo of the anterior forearms with perifollicular repigmentation process (brown dots).

The cause of the acquired hypomelanosis is unknown but it is often familial. Mechanisms of pigment loss are not well understood. One- to 2-year-old animals develop leukoderma on eyelids, periocular skin, muzzle, nares, genitalia, anus perineum, and inguinal region.