The reaction tube is automatically inserted into the I-CORE module after the cartridge is loaded into the instrument. P.O Box 1016 EP 0 872 562, Japanese Patent No. There are a number rapid tests in the pipeline, but none so far have been approved. Conveyed with the purchase of real-time thermal cycler are the licensing rights to perform the patented real-time polymerase chain reaction process on the GeneXpert® under Applera's European Patent No. A total of 113 nasopharyngeal swabs from remnant patient samples were tested, including 88 positives spanning the full range of observed Ct values on the cobas assay. What dyes can be used on the GeneXpert Biothreat system? GeneXpert System technology is the cornerstone of our unique approach to a molecular diagnostics product suite, which allows us to offer a complete menu of tests on a single, fully scalable, consolidated workstation. MSF has been involved in TB care for over 30 years, often working alongside national health authorities to treat patients in a wide variety of settings, including chronic conflict zones, urban slums, prisons, refugee camps and rural areas. If we target 5 GeneXpert machines per …

The TB test for the platform currently costs $9.98 per cartridge for low- and middle- income countries. Also, some filters may remove the .gxx extension. 1999-2019: 20 Years of Advocacy in Action. However, for Ct values >30, positive agreement was 34.3% for ID Now and 97.1% for Xpert. I also represent that the information disclosed in the submission is wholly original to me, that I am the sole owner of all the information disclosed in the Submission, and that no interest in the information in the Submission has been granted to or acquired by others. Hyderabad, India – 1 November 2019 – Activists disrupted a session at the 50th Union World Conference on Lung Health to demand that the diagnostics corporation Cepheid halve the price of its tuberculosis (TB) tests GeneXpert MTB/RIF and MTB/RIF Ultra to US$5. The GeneXpert system can only be used with the GeneXpert cartridge. I agree to rely solely on my patent rights (if any) with respect to any claim I might have with respect to the Submission. However, we have an Ethernet switch (Cepheid part number 800-0038) to allow up to 4 GX instruments to work with a computer system. We can’t think of better words than “game changing”. Sign up to stay updated and find out how you can get involved. GENEXPERT-IV AUTOMATED REAL TIME PCR TECHNOLOGY ITC (PATIENT CARE ITEMS) … As of 6 August 2012, the cost of a test cartridge in countries eligible for concessional pricing is 9.98 USD. Our GeneXpert ® family of systems have set a new standard in workflow flexibility, 24/7 testing accuracy, and user-friendly design — delivered in an astonishingly beautiful and compact package.. The computer can support 1 GX instrument. 1500+ Genexpert tests conducted yearly. 1.A: Frequency distribution of cycle threshold (C t) values for positive patient samples by Roche cobas SARS-CoV-2 (blue), Cepheid Xpert Xpress SARS-CoV-2 (orange) and Abbott ID Now SARS-CoV-2(gray) assays.Roche cobas Target 1 (ORF1) C t values were rounded to the nearest whole number. Médecins Sans Frontières Cepheid is responding to the global need with rapid and easy-to-use tests that enable healthcare providers to obtain a result within an hour of obtaining a patient sample. Since its inception in 2013, the GCTA has contributed significantly to the global TB agenda through its network of over 300 members affected by TB. GCTA is composed of regional, national, and sub-national coalitions of TB advocates, including Activists Coalition on TB – Asia-Pacific (ACT AP) in the Asia-Pacific region, Activists Coalition on TB in the Africa region, TB People in Europe, and Red de Personas Afectadas por Tuberculosis en Latino América y El Caribe (REDTBLAC) in the Americas. I acknowledge and agree that Cepheid has not solicited the Submission, and that I make it voluntarily. Compared to cobas, the overall positive agreement was 73.9% with ID Now and 98.9% with Xpert.

Book this really important test at highly rated labs like at your local top quality labs through us at up to 50% discount. Cepheid is responding to the global need with rapid and easy-to-use tests that enable healthcare providers to obtain a result within an hour of obtaining a patient sample.

While Xpert showed high agreement with cobas across a wide range of viral concentrations, this study highlights an important limitation of ID Now for specimens collected in viral or universal transport media with low viral concentrations. As of 30 June 2013, 1,402 GeneXpert systems (comprising 7553 modules) and >3 million Xpert MTB/RIF cartridges had been procured in 88 of the 145 countries under concessional pricing. GENEXPERT-IV AUTOMATED REAL TIME PCR TECHNOLOGY ITC (PATIENT CARE ITEMS), GENEXPERT IV R2 4 MODULE CONFIGURATION - GXIV-4-L (S/L NO:810943 ), GXIV-2-D GENEXPERT IV R2 2MODULE CONFIGURATION D ( GENETIC ANALYZER ), GXIV-4-L GENEXPERT IV R2 4 MODULE CONFIGURATION L (GENETIC ANALYZER), GENEXPERT IV R2 2 MODULE CONFIGURATIOIN D P/N GXIV-2-D, S/N810288 (LAB INSTRUMENT), GENEXPERT IV R2 2 MODULE CONFIGURATION DCHEMISTRY OR HEMATOLOGY ANALYZER. This would allow for up to 16 samples to be run on the GeneXpert System. The major cost drivers were equipment costs and reagents (mainly the cost of the GeneXpert machine–decreasing with increasing batch size–and the Xpert cartridge) while overhead and direct staff hands-on cost had minimal impact. “Cepheid’s TB tests should be made affordable. 20 Years of Advocacy in Action - JOIN US!

Rue de Lausanne 78 In June 2012 the organisation UNITAID approved funding of $30 million with … Reaction tube-Enables rapid thermal cycling and optical excitation and detection of the tube contents.

It is time that Cepheid start prioritising people over profit, and become accountable to communities affected by TB by lowering the price of GeneXpert tests to $5. But our GeneXpert® family of systems have set a new standard in workflow flexibility, 24/7 testing accuracy, and user-friendly design — delivered in an astonishingly beautiful and compact package. The GeneXpert ® family of systems offers a single, standardized solution capable of running multiple sexual health tests and respiratory tests on one space saving system. https://doi.org/10.1016/j.jcv.2020.104428. According to the WHO, current volumes of GeneXpert tests have to be expanded 10-fold in order to provide access to all people that need testing for TB in the 30 high burden countries. E-mail: access(at)msf.org. It is time that Cepheid start prioritising people over profit, and become accountable to communities affected by TB by lowering the price of GeneXpert tests to $5.”, “It is critically important for doctors and nurses in the field to be able to rapidly diagnose people with TB or multidrug-resistant TB in order to treat them quickly and effectively. Since 2012, the cost of GeneXpert tests in the public sector have been locked into the price of $9.98 per cartridge, which was the result of a buy-down agreement in which Unitaid, the United States government, and the Bill & Melinda Gates Foundation paid Cepheid $11.1 million to reduce the price of GeneXpert cartridges from $16.86.

Contact Cepheid Customer Service to order the assay specific cartridges: 1-888-838-3222 Option 1. Each cartridge consists of the following components: Please refer to the website for further details regarding the GeneXpert® technology.

Detailed Analysis & Trends of: What dyes can be used on the GeneXpert DX system?

Cepheid developed the GeneXpert testing platform and Xpert MTB/RIF tests over the past two decades with substantial public and philanthropic funding, which included an estimated $120 million from the US Department of Defense, $45 million from the US National Institutes of Health (NIH), and over $20 million via the Foundation for Innovative New Diagnostics (FIND), with funding largely from the Bill & Melinda Gates Foundation. The GeneXpert® Dx system can run a number of assays developed by Cepheid. The GeneXpert cartridges are not supplied with the Cepheid. After the sample is processed, it is mixed with PCR reagents and moved into the integrated reaction tube. I agree to resolve any dispute with Cepheid arising from or relating to my Submission under the laws of California, being Santa Clara Count in California USA, the agreed court venue. The Global Coalition of TB Activists (GCTA), Médecins Sans Frontières (MSF) and Treatment Action Group (TAG) were among the organisations that signed on to an open letter, endorsed by 127 organisations and individuals, demanding that Cepheid lower the price of GeneXpert tests to $5, inclusive of service and maintenance. The SARS-CoV-2 pandemic has created an urgent and unprecedented need for rapid large-scale diagnostic testing to inform timely patient management.

We are science-based treatment activists working to expand and accelerate vital research and effective community engagement with research and policy institutions. In arrangements made a decade ago, prices for the GeneXpert device, which normally costs about US$17,000, as well as cartridge prices were reduced, for 145 eligible low- and middle-income countries. GXIV-4-L(GENEXPERT IV R2 4 MODULE CONFIGURATION L)(GENETIC ANALYZER) WITH STANDARD ACCES. When emailing an archive run, do not use a Yahoo account or a MAC computer. Access to affordable Xpert cartridges would go a long way in finding the millions of missing TB patients who continue to remain undiagnosed and are unable to access treatment,” said Dr. Vivian Cox, TB Advisor at MSF. What symbology is supported with the 2D scanner? The new Xpert® MTB/RIF Ultra cartridge can be used on the same GeneXpert® equipment (GeneXpert® instrument, computer, monitor, keypad, bar code reader) and will be available at the same concessional price of USD 9.98 for all eligible countries. Cost per kit (10 tests): US$ 198.00. For 8 hours working hour in a day, you can run 36 test. The cost for a cartridge is $19.8 (N7,128). The cost of GeneXpert per cartridge is US$17 universally except for some high TB burden and low income countries which receive a discounted cost of about US$10 .

I agree that Cepheid shall have no obligation to specify or explain the reason for any decision Cepheid may make with respect use or non-use of the information in my Submission, and that Cepheid shall have no obligation to incorporate or use any information in the Submission in any product. Do not replace or reconfigure any of the components. The concessional price for a GeneXpert system is currently 32,000 USD for a four module instrument. Improving patient outcomes is the primary goal of any diagnostic system.